A train derailed near Cement Siding in Bulawayo on Saturday.
A locomotive pulling another went off the railway tracks under unclear circumstances, and they both overturned.
The crew had been taken to a local hospital for treatment, but the state of their injuries could not be ascertained.
The service was being operated by the Beitbridge Bulawayo Railway company. The locomotives were due to pull wagons loaded with cement from PPC Cement, about 5km east of the city.
It was not clear what the cause of the accident was, but pictures from the scene showed a broken track – although it was not clear whether this had happened before or after impact.
It is the second derailment within a week after another goods train hit a truck and derailed near Beitbridge on the tracks leading to Harare.
The Beitbridge-Harare road was blocked for two days, before engineers from BBR managed to move the wagon blocking the road.